Raman spectroscopic detection of sub-picomolar DNA by coupling silver catalyzed silver deposition with circular strand-replacement polymerization on magnetic nanoparticles.
نویسندگان
چکیده
A novel strategy of dual signal amplification was developed using circular strand-replacement DNA polymerization with a molecular beacon as a switch and silver enhancement on magnetic nanoparticles for the specific Raman spectroscopic detection of DNA down to the sub-picomolar level.
منابع مشابه
Alumina coated Ag nanocrystal monolayer as surface-enhanced Raman spectroscopy platforms for direct spectroscopic detection of water splitting reaction intermediates
A novel Ag-alumina hybrid SERS platform has been designed for the spectroscopic detection of surface reactions in steady state. Single crystalline and faceted silver (Ag) nanoparticles with strong light scattering were prepared in large quantity, which enables their reproducible self-assembly into large scale monolayers of Raman sensor arrays by Langmuir-Blodgett technique. The close packed sen...
متن کاملA cytosine-rich DNA decorated gold nanoparticles surface enhanced Raman-scattering platform for sensitive and selective detection of silver ions.
In this work, we developed a label-free, homogeneous surface-enhanced Raman-scattering (SERS) platform for the rapid, simple and sensitive detection of Ag(+) by using the unmodified gold nanoparticles (AuNPs). It utilizes the different absorption properties of single-strand DNA (ssDNA) and double-strand DNA (dsDNA) on citrate-coated AuNPs and specific interactions between Ag(+) and cytosine-cyt...
متن کاملCoating Of Silver Nanoparticles by Sputtering Method on Glass Substrates as Surface-Enhanced Raman Spectroscopy (SERS) Biosensor for Detection of Whey Protein
This article has no abstract.
متن کاملSurface Enhanced Raman Scattering of Crystal Violet with Low Concentrations Using Self-Assembled Silver and Gold-Silver Core-Shell Nanoparticles
The active substrates in surface enhanced Raman scattering (SERS) spectroscopy were prepared through self-assembly of nanoparticles on functionalized glasses. Colloidal silver nanoparticles (Ag NPs) were prepared chemically in two different sizes by reduction of AgNO3 using trisodium citrate and sodium borohydride. Gold–silver core–shell nanoparticles were also prepared to compare between the o...
متن کاملCatalytic Aerobic Oxidation of Alkenes by Ag@Metal Organic Framework with High Catalytic Activity and Selectivity
By coupling of Fe2O3@SiO2 particles with metal organic Framework (MOF) the magnetic MOF structure was fabricated. Precipitation and hydrothermal methods were applied for synthesis of core and MOF. Silver nanoparticles were deposited on nickel based metal organic framework surface and magnetic Fe2O3@SiO2@MOF@Ag was obtained. Because of strong coupling between silver nanoparticles and metal organ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 48 86 شماره
صفحات -
تاریخ انتشار 2012